Advanced Course: Essential Knowledge in Peptides for Age Management Medicine – Final Exam

A peptide bond is formed by what reaction

According to the Human Proteome Map how many peptides do we approximately have?

What type of receptors are oxytocin receptors, calcium sensing receptors, and melanocortin receptor?

Which hormones are peptides

G protein coupled receptor is activated by

Peptides are

A peptide bond is

True or False: In the oxytocin nasal spray trial in pre and post-menopausal women showed that oxytocin was better than placebo in improving female sexual dysfunction.

The receptor that requires the phosphorylation of the receptor like the vascular endothelial growth factor (VGEF), nerve growth factor (NGF) and insulin like growth factor (IGF) are what type of receptors

Epithalon has been shown in a mice and rat study

A recommended dosing of Epithalon

True or False: In the Bremelanotide trials there was no side effects of nausea, flushing, or headaches?

Melanontan 1 or Afamelanotide has been shown to improve what skin condition

Bremelanotide PT-141 is a derivative of which peptide

Intranasal use of Bremelanotide PT 141 increased what

Suggested first dosing of Bremelanotide PT 141 is

Recommend dosing of DSIP with Glycine

In December 2017 the FDA has approved Macimorlelin an oral agent to diagnose low growth hormone. Is Macimorelin a

The advantages of using peptides to stimulate growth hormone versus using human growth hormone

CJC-1295 an analog of

In a 2006 study with CJC-1295 with DAC looking at lipodystrophy in HIV patients there was one adverse side effect

Growth hormone releasing peptides (GHRP) stimulates what in the pituitary to release Growth hormone?

Which peptides stimulates the Ghrelin receptor?

Tesamorelin recommended dosing is

What is the common dose of CJC-1295 non Dac with ipamorelin?

True or False: BPC-157 has been shown in animal study to heal a detached achilles.

BPC 157 increases which type of collagen the most?

The mechanism of action of BPC 157 might be

BPC 157 has been shown to

True or False: There is an animal study showing that BPC 157 healed a transected sciatic nerve

In animal phase 2 study the lethal dose of BPC 157 to kill 1% was

True or False: BPC 157 can help with chemical or alkali burns

True of False: BPC 157 has no role in helping with the recovery of traumatic brain injury

Typical dosing with BPC 157 for an acute musculoskeletal injury would be?

Cerebrolysin was discovered by An Austrian professor in 1949 and it contains

Recommended starting dose of MK-667 is

True or False: In the meta analysis of 6 randomized double blind placebo controlled studies on Cerebrolysin for mild to moderate Alzheimer’s disease, Cerebrolysin did not improve on cognitive function

Combination of Cerebrolysin and Donepezil (Aricept) showed

Cerebrolysin in first degree relatives with Alzhemier’s showed after 1 month of Cerebrolysin at 20 m/ day for 1 month

Dosing of Cerebrolysin in studies

True of False: Cerebrolsyin is mixed in 250 cc of normal saline or ½ normal saline

Semax was discovered from what country

Semax is analogue of which hormone

Semax improved recovery in stroke, what doses did they use?

Semax can be delivered

Selank main effect is that it helps with

True or False: Selank increases BDNF

Selank influences the gene expression of what

Selank can be delivered

Selank dosing

What type of T cell promotes a tolerogenic environment and can be of benefit in the treatment of autoimmune diseases?

Which of these interleukins is responsible for promoting a tolerogenic environment?

This T helper cell population plays a role in eradicating extracellular fungi and bacteria. They have also been identified as playing a major role in autoimmune diseases:

This peptide can block the release of IL6, IL12, NF-Kb, TNFa and can increase regulatory T cells.

VIP affects immune function in which of the following ways?

Which of these is not a cell growth cycle checkpoint?

Metenkephalin stimulates which of the following cancer inhibitory pathways?

Which of the following doses of Metenkephalin has been studied clinically?

What protein needs to be expressed in cancer cells for PNC 27 to exert its anticancer effects?

GHK-cu’s anticancer mechanism of action is:

Which of these is synthetic thymic peptide?

TA1 has not been studied as a treatment for which of these infectious diseases?

Thymosin beta 4 could have a protective role in sepsis through the modulation of which protein:

True or false: Autologous stem cell injections have been shown to increase TB4 levels in treated subjects

True or false: Thymosin Alpha 1 has been shown to reduce mortality in the treatment of sepsis

Although multiple dosing regimens have been studied with TA1, an accepted dosing regimen in cancer management is:

A suggested dosing regimen for PNC 27 is:

VIP for autoimmune diseases is usually dosed at:

An acceptable TB4 dose is:

Although no formal GHK-cu dosing for cancer has been established, anecdotal results have been observed at: