Florence Comite, M.D.
Owner & CMO, Comite Center for Precision Medicine, New York, NY
Recipient, Alan Mintz Award for Clinical Excellence
Member, AMMG Planning Committee
Florence Comite MD is a clinician scientist, endocrinologist, and the leading expert in the fields of healthy longevity and precision medicine. She is internationally known for her expertise in leveraging proprietary clinical and wearable data to detect, predict, and reverse biological aging and the disorders of aging, and optimize health and vitality.
A graduate of Yale School of Medicine, where she was a faculty member for twenty-five years with a triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology), Dr. Comite trained at the National Institutes of Health. In 1992, she pioneered the nation’s first center for women’s health at Yale, redefining integrative care for women.
In 2005, Dr. Comite founded the Comite Center for Precision Medicine & Healthy Longevity in New York City, where she established a clinically proven, academic approach to personalized healthcare structured around the individualized clinical process known as Nof1™, where each patient is treated as a single subject clinical trial. In recent years, the Center has expanded to Palo Alto and Miami Beach. She also founded the first physician-led artificial intelligence app. Trained on decades of her proprietary real-world research, it’s a powerful personalized tool to help people optimize their healthspan.
Dr. Comite has published original research and articles in numerous clinical journals, such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. She is known for her seminal research in children, women, and men proving that our entire system is critical in aging and disease. In 2013 she authored a bestselling book, Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life, with a primary focus on androgen deficiency and vitality in aging men. Data from her clinical research and decades of clinical practice inform Dr. Comite’s new book, Invincible: Defy Your Genetic Destiny to Live Better, Longer, which will be published by Little Brown, Spark in April 2026.