JUNE 2025 | Vol. 20, No. 2
FEATURED ARTICLES
Uncontrolled, chronically high blood pressure (hypertension) contributes to a host of complications known collectively as hypertensive heart disease, which accounts for approximately 10 million deaths annually. Before pharmaceutical drugs such as beta blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors were available, a natural substance known as reserpine, derived from Rauwolfia plants, was widely used to manage hypertension. A few small randomized controlled trials have shown promising results from the use of reserpine or Rauwolfia for hypertension, corroborating a decade’s worth of clinical observation.
A study show mice injected with a protein called Klotho lived almost 20% longer than their untreated peers. Beyond just extending life, these mice maintained better muscle strength, bone density, and brain function well into old age—essentially slowing multiple aspects of aging simultaneously..
LATEST AGE MANAGEMENT MEDICINE NEWS
Spit Science: Why Saliva Is A Great Way To Detect Disease
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Top Aging Expert Says These 4 FDA-approved Drugs Hold Promise for Extending Life
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Newly Discovered Mechanism of Mitochondrial Dysfunction in Obesity May Drive Insulin Resistance and Type 2 Diabetes
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Scientists Find Promise in a New Peptide Drug to Combat a Deadly Brain Cancer
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Depression is Linked to an Increased Risk of Dementia in Both Mid and Later Life, Finds Study
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Women’s Health
New Study Suggests Hormone Therapy May Improve Certain Heart Health Markers in Menopausal Women
Korin Miller
New research found that women in menopause who took oral hormone therapy showed improvements in certain biomarkers of cardiovascular health, including cholesterol.
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PATIENT ASSESSMENT & DIAGNOSTICS
New Blood Test Diagnoses Alzheimer’s Disease and Measures How Far It’s Progressed
Melissa Rudy
Several blood tests have been shown to accurately diagnose Alzheimer’s disease, but now a new test has emerged that can gauge how far it has progressed.
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HORMONE REPLACEMENT THERAPY & AGE MANAGEMENT MEDICINE
New Advances in Hormone Replacement Therapy Set to Transform Care
Charles P. Virden, M.D. and Lisa Stehno-Bittel
A novel approach using hormone-filled microbeads in hydrogels for steady, extended release may solve the problem of existing delivery methods that struggle with poor adherence and inconsistent hormone delivery.
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BRAIN HEALTH
Anti-amyloid Drug Shows Signs of Preventing Alzheimer’s Dementia
Science X staff
An experimental drug appears to reduce the risk of Alzheimer’s-related dementia in people destined to develop the disease in their 30s, 40s or 50s.
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OBESITY & WEIGHT LOSS
Scientists May Have Discovered Why the Pounds Come Back After Losing Weight
Shiv Sudhakar
Researchers say that fat cells influence abnormal metabolic pathways in the body long after pounds are shed, which could make it more likely for people to regain weight.
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PRACTICE MANAGEMENT PERSPECTIVES
2 in 3 Physicians Are Using Health AI—Up 78% from 2023
Tanya Albert Henry
Physicians’ use of health care augmented intelligence (AI) for certain tasks nearly doubled in just one year, and enthusiasm for the technology is growing even if some doubts still linger, says a recently released AMA survey.
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