OCTOBER 2025 | Vol. 20, No. 3
FEATURED ARTICLES
An estimated 42% of Americans over 55 are projected to develop some form of dementia, according to the National Institutes of Health. But 2025 has proven to be a year of dramatic advances in research, diagnosis and treatment of cognitive decline, dementia and Alzheimer’s. Here we present details about some of the recent developments, and preview in-depth discussions at the upcoming Age Management Medicine Conference.
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AMMG returns to the Grand America Hotel in Salt Lake City, Utah in November, for the 39th Clinical Applications for Age Management Medicine Conference—once again presenting a wide range of groundbreaking research and treatment options for practitioners determined to advance longevity through evidence-based strategies and technology.
The next big thing in personal healthcare gaining momentum right now is longevity clinics, giving patients deeper knowledge and insights into their own biology. It is out of the price range of many people, but continued advancements in technology may change that.
LATEST AGE MANAGEMENT MEDICINE NEWS
Fitness Expert Reveals 6 Pillars of Strength Training that Older Adults Should Master
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Could Psilocybin Be the Magical Ingredient for a Longer Life?
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mRNA Vaccine Shows Promise for Treating Age-Related Macular Degeneration
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Researcher Developing Pancreatic Cancer Treatment that Targets Newly Identified Protein
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Older Adults Can Bounce Back to Thriving Health, Study Finds
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Women’s Health
Effect of Early Menopause and Hormone Replacement Therapy on Aortic Stenosis Progression
Abdoun, Tastet, Bédard, Arsenault, Pibarot, Clavel
Early menopause has been associated with several cardiovascular diseases, but its effect on the progression of aortic stenosis (AS) remains unknown. This analysis examines the effect of early menopause without hormone replacement therapy on the progression of AS in postmenopausal women with AS.
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FITNESS IN MEDICINE
Scientists Discover Exercise Creates ‘Youth Molecule’ That Could Reverse Aging in Muscles and Bones
Study Finds Staff
Research out of South Korea reveals that when you exercise, your muscles release a powerful protein that acts like a biological time machine, potentially reversing age-related decline in both muscle and bone strength.
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PATIENT ASSESSMENT & DIAGNOSTICS
DNA Markers Found to be Highly Accurate at Predicting Human Age
Rebecca Shavit
A groundbreaking study by researchers at Weill Cornell Medicine and epigenetics company TruDiagnostic has unveiled new DNA markers associated with retroelements—remnants of ancient viral genetic material within our genome—that act as highly accurate epigenetic clocks for predicting chronological age.
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HORMONE REPLACEMENT THERAPY & AGE MANAGEMENT MEDICINE
Growth Hormone Replacement Therapy in Heart Failure With Reduced Ejection Fraction: A Randomized, Double-Blind, Placebo-Controlled Trial
Marra, D’Assante, De Luca, et al
Growing evidence suggests that reduced activity of the growth hormone/insulin-like growth factor axis is common and associated with poor clinical status and outcome in heart failure, while preliminary results of growth hormone deficiency correction in heart failure showed an improvement in quality of life, cardiac structure and function, and cardiovascular performance. This double-blind, randomized, placebo-controlled trial aimed to evaluate the cardiovascular effects of 1 year of GH replacement therapy in a cohort of patients with heart failure and reduced ejection fraction.
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PERSONALIZED & PRECISION MEDICINE
The Pioneering Therapy That Could Roll Back the Rigors of Aging
Sarah Knapton
A groundbreaking new therapy—mitochondrial transplantation—that aims to recharge cells with “batteries” from the placenta of newborns, is being tested in humans. It could treat incurable diseases and keep bodies younger longer.
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