Thursday, November 4th
Workshop: Senotherapeutics for Age Management Medicine
Cellular senescence is one of the main driving forces for aging and organ dysfunction. As such, the field of Senolytics is poised to become the next big niche in Age Management Medicine. It is important for practitioners to understand how to assess body senescence burden and how to employ adequate senolytic strategies. This half-day workshop will teach healthcare practitioners the fundamentals for properly integrating senolytic treatments into their clinical practices. We will cover everything from the basic biology of cell senescence to testing and treatment protocols. Practitioners will leave the workshop with the necessary tools and knowledge required to start offering senolytic therapies in their practice.
Time |
Presentation |
|---|---|
| 1:30 – 2:15 pm | Understanding the Fundamentals of Cellular Senescence: Why it Happens and How it Affects Health Jin-Xiong She, Ph.D. Professor, Augusta University. Founder & CEO, Longevity Testing, Jinfinti Precision Medicine This lecture will review the biological mechanisms of cellular senescence. We will discuss cellular quiescence, geroconversion and final steps towards irreversible senescence. Additionally, we will describe the senescence associated secretory phenotype (SASP) and its impact on cellular microenvironment. |
| 2:15 – 2:50 pm | Testing for Cellular Senescence Luis Martinez, M.D., MPH President, XanoGene Clinic, San Juan, Puerto Rico President, Regenera Global, Ponce, Puerto Rico Recent advances have made testing for cellular senescence a more available and applicable test for physicians to incorporate in their Age Management Practice. This lecture will cover all the biomarkers and laboratory testing methods currently available for clinicians. The pros and cons of different testing approaches will be discussed. Additionally, an integrated model for assessing cellular senescence will be presented. |
| 2:30 pm | Exhibits Open |
| 2:50 pm – 3:30 pm | Break / Visit Exhibits |
| 3:30 – 4:00 pm | Senolytics- What Are They and Do They Work Luis Martinez, M.D., MPH President, XanoGene Clinic, San Juan, Puerto Rico President, Regenera Global, Ponce, Puerto Rico Senolytics, and more broadly senotherapeutics, can now be offered in clinical settings. This lecture will discuss the mechanisms of action by which senolytics work. We will list the different senolytics currently available for clinical use. Additionally, we will discuss other senotherapeutic strategies such as senomorphics, geroprotec-tors and SASP inhibitors. |
| 4:00 – 4:45 pm | Senolytic Treatment Protocols Luis Martinez, M.D., MPH President, XanoGene Clinic, San Juan, Puerto Rico President, Regenera Global, Ponce, Puerto Rico These lectures will review treatment protocols for incorporating senolytics and senotherapeutics into clinical practice. A review of clinical studies for the different treatments will be presented. Finally, specific case studies will be shown with an evidence-based approach for treatment selection. |
| 4:45 – 5:30 pm | Case Discussion and Review of Protocols Luis Martinez, M.D., MPH President, XanoGene Clinic, San Juan, Puerto Rico President, Regenera Global, Ponce, Puerto Rico Clinical Cases will be presented and include a review and discussion of the protocols used for treatment |
| 5:30 – 7:00 pm | AMMG Welcome Reception Open to all conference attendees, spouses, and guests Held in Conference Networking and Exhibits Center |