Advanced Course: Essential Knowledge in Peptides for Age Management Medicine
7.0 Hours – For Certificate Participants
The use of Peptides and Peptide Therapies has experienced exponential growth over the past few years. Their uses range from impacting hormonal change, to antibiotic properties, to treatments for conditions of aging such as cancer, cardiovascular health, memory & brain health and sexual function. AMMG in conjunction with the Clinical Peptide Society have an educational mandate is to fill the scientific and medical knowledge gaps for physicians and healthcare professionals. This course is a focused track on essential knowledge in the clinical use of peptides for Age Management and will include discussions regarding those Peptides which are approved in the United States and can be compounded and those which are not. At the completion of parts 1-3 of this course, 15.25 hours of content and successfully passing the examination applicants will receive a Certificate of Completion for their study in Peptides.
In conjunction with the Clinical Peptide Society
*COMPLIANCE DISCLOSURE: AMMG has made every effort to have all lectures and statements made regarding Peptides comply with all FDA and State and Local laws. There are some Peptides which the FDA has not approved for compounding. This is a new and potentially changing area of medicine and we encourage you to frequently check for new policies, laws and rules which may apply to your practice and to strictly adhere to all laws which apply.
Curriculum
The world of peptides therapy is a growing field in medicine ranging from improving skin care, to growth hormone, to one’s immune system, to name a few. On Pub Med there are over 2.5 million articles on peptides. It is estimated that humans have over 250,000 peptides and we only understand a fraction of them. Peptides are chains of amino acids linked together by a polypeptide bond. The formation of a polypeptide bond by a dehydration synthesis will be reviewed. The difference between a peptide and a protein will be delineated. In addition the mechanism of action on how peptides work will be reviewed. The history of peptides will be covered and also knowing which hormones are peptides will be reviewed. Peptides have pleotropic effects and during the conference this subject will be addressed.
Growth hormone is an essential hormone in lowering body fat, improving on lipids, keeping muscles healthy and improving on bone density. Adult growth hormone deficiency symptoms will be reviewed and the association of higher mortality with growth hormone deficiency. Unfortunately the treatment with recombinant human growth hormone is not covered under most insurance plans, and it is cost prohibitive for most people. There is an alternative to the expensive recombinant human growth hormone most commonly used for boosting IGF-1 and it has the advantage of inducing all five of the hGH isoforms rather just the one that is found in the synthetic form. CJC-1295, Ipamorelin, GHRP-6, Teslomorelin and others are peptides that have been shown to help improve IGF-1 levels.
Millions of Americans suffer from autoimmune diseases. Immune dysregulation, a universal characteristic of autoimmune diseases, can be targeted through the use of specific peptides. This lecture will present the rationale for utilizing peptide therapy in the management of autoimmune diseases. T cell modulation, cell predominant shifts, OGF axis and other mechanisms of action will be highlighted. VIP, thymosins and other peptides will be covered. Cases and protocols will be discussed.
BPC-157 was discovered in the 1990s in gastric juice. However I give credit to Dr. Pavlov in Russia in the early 1900s since he was manufacturing gastric juice from dogs to help heal many alignments. At that time they did not have the technology to detect BPC-157. BPC-157 has been studied extensively in animals and has been shown to improve on healing the body. Studies with BPC-157 have been shown to heal a severed tendon, nerve, and also ulcers. Although there are no human clinical trials the body builders has been using BPC-157 experimentally to repair their torn muscles, tendons and ligaments. In this lecture the published studies of BPC-157 ranging from colitis, inflammatory bowel disease, systemic steroid impaired muscle healing, bone defect, periodontitis, and others will be reviewed. Although the FDA has not approved this peptide, BPC-157 has been used worldwide.
Millions of Americans suffer from autoimmune diseases. Immune dysregulation, a universal characteristic of autoimmune diseases, can be targeted through the use of specific peptides. This lecture will present the rationale for utilizing peptide therapy in the management of autoimmune diseases. T cell modulation, cell predominant shifts, OGF axis and other mechanisms of action will be highlighted. VIP, thymosins and other peptides will be covered. Cases and protocols will be discussed.
Advances in peptide biology have shed light on multiple pathways which can be targeted for therapeutic interventions with the use of peptides. These can be incorporated as part of a comprehensive cancer management approach. The lecture will discuss peptide classes, mechanisms of action and proposed protocols for incorporating peptide therapy in the treatment of cancer patients. Peptides including Met-Enkephalin, PNC 27, P18 among others will be discussed. Oncostatic and oncolytic characteristics will be reviewed.
An estimated 6 million Americans have Alzheimer’s disease, 10 million people worldwide with Parkinson’s, 3 million Americans suffer from traumatic brain injury (TBI), and approximately 800,000 will suffer from a stroke each year. There are peptides that have been shown to have neuroregenerative properties that have clinical studies in strokes, traumatic brain injury, Parkinson’s and in Alzheimer’s disease. There are many mechanisms that are involved with neurodegenerative diseases to traumatic brain injury. Inflammation in the brain, excessive oxidative stress, mitochondrial impairment, and excitotoxicity are common theme that can lead to damage or death of the neuron or myelin. Peptides have been shown to reduce inflammation, reduce oxidative stress, increase the production of brain derived neurotrophic factor and also increase the production of neurons. The peptides of Thymosin Beta 4, BPC-157, Cerebrolyin, Dihexa and Semax will be covered.
Alpha melatonin stimulating hormone analogues, including PT 141 and Melanotan, can act on multiple melanocortin receptors. As such, they have been studied and are currently being used for multiple indications, including increasing libido, altering skin pigmentation and modulating food intake. Epitalon is a pineal peptide, originally studied in Russia. It has been shown to activate telomerase, restore melatonin secretion and reduce mortality in users. This lecture will review both pineal and pituitary physiology as they relate to these peptides. Melanocortin receptors and neuropetides will be discussed.
FACULTY
- Assistant Professor of Internal Medicine, University of Central Florida, College of Medicine, Orlando, FL
- Founder, Institute for Hormonal Balance, Orlando, FL
- Member, AMMG Conference Planning Committee
- Co-Founder, Clinical Peptide Society
Dr. Edwin Lee is an endocrinologist, author and international speaker. Dr. Lee founded the Institute for Hormonal Balance, Orlando, FL in 2008, is board certified in Internal Medicine, Endocrinology, Diabetes and Metabolism, and has completed special training in Regenerative and Functional Medicine. Currently, he is the assistant professor of Internal Medicine at the University of Central Florida College of Medicine. In addition to writing his award winning books, “Your Amazing Heart,” “Your Awesome Brain,” “Feel Good Look Younger: Reversing Tiredness Through Hormonal Balance,” and “Your Best Investment: Secrets to a Healthy Body and Mind,” Dr. Lee has published many articles on internal medicine and endocrinology. He was also an author in the fourth edition of Textbook of Critical Care. His passion is healthy living and he practices what he preaches. He enjoys participating in open water swimming, cycling, hiking and Aquabike competition. Dr. Edwin Lee resides in Orlando, FL with his wife and 2 teenage boys.
CME Disclosure: No Relevant Financial Interest in any Products or Services to be discussed
- President, XanoGene Clinic, San Juan, Puerto Rico
- President, Regenera Global, Ponce, Puerto Rico
- Co-Founder, Clinical Peptide Society
Dr. Luis Martínez is a Regenerative Medicine and Cell Therapy specialist, clinical researcher and biomedical consultant. He earned his medical degree at The Ponce School of Medicine and completed his residency training at the prestigious University of Pennsylvania. He also completed an Advanced Training Course in Stem Cells in Cancer at the Ponce Health Sciences University/ Magee Research Institute consortium. He is board certified in Clinical Lipidology. Dr. Martinez holds a Masters of Public Health with a concentration in Epidemiology and is fellowship trained in Biosecurity. He is the president of Xanogene Clinic, which specialized in Regenerative and Age Management Medicine. He also founded and presides over Regenera Global, a multinational corporation specializing in biotech product development, research, and clinical consulting.
Dr. Martinez has advised and helped set up various clinics and laboratories in Latin America within the Regenerative Medicine space. He also serves on the advisory board for various Biotech companies and professional societies. He is actively involved in educating and training physicians in multiple aspects of Regenerative and Age Management Medicine.
CME Disclosure: No Relevant Financial Interest in any Products or Services to be discussed
Instructions for Completing your Certificate
Completing all steps is a requirement in order to qualify to receive your Certificate.
- Before watching Part 2 videos participants are required to have completed Clinical Use of Peptides and Peptide Therapies – Full Course
- After completing the Part 2 videos “Go to Final Exam” and complete the entire Final Exam
- You must receive a score 75% or higher in order to be eligible for an Advanced Course Certificate
- AMMG will mail your Advanced Course Certificate