Agenda April 2024

Building Your Practice with DEXA

Presented by Tony Orlando

Non-CME Symposium Sponsored by DEXA Plus

Open to all attendees and includes a complimentary lunch

There is a paradigm shift occurring in aesthetic medicine. Some celebrities have publicly announced that they have had their hyaluronic acid fillers dissolved and consumers are now opting for a more natural approach. Using PRP to rejuvenate skin is not new but new protocols have been developed and Dr. Polit will explain the techniques that we are now using to deliver what we call “regenerative aesthetics.” PRF gel is used to time release growth factors for lasting rejuvenation. PRP Plasma Gel is a way we can create large volumes of natural filler with the added benefit of growth factors from a double spun PRP. A demonstration of a PRP facial and the gel warmer will accompany the talk.  A demonstration of a PRP facial and the gel warmer will accompany the talk.

Many Aesthetics providers are reluctant to add PDO threads to their practice fearing that it is too complicated. This is good news for those willing to learn some basic techniques to get started and offer something that the competition does not have. Dr. Song will explain the theory behind the absorbable threads and discuss the different types of threads that you can use in your practice. A live demonstration of smooth thread placement and a video demonstration of barbed thread placement will accompany the talk.

There are many different approaches to treating hair loss, from PRP injections to hair transplants. The problem most practitioners face is that the results are unpredictable and inconsistent. Learn how you can incorporate a consistent and profitable hair treatment program into your practice. A live demonstration of Microneedling growth factors into the scalp will accompany the talk.

Advanced Aesthetic Technologies

Presented by Tony Howard

Non-CME Symposium Sponsored by Refine USA

Open to all attendees and includes a complimentary lunch

There are many advantages to combining treatments the skill is to know what goes with what and why is that a benefit to the patient. There are also many fit falls if you combine the wrong things as that may put you at risk with your insurance company. We will advise you on your menu selections, provide supporting data as to benefit and provide demonstrations utilizing different modalities.

With his deep scientific knowledge, Dr. Song will explain how this technology can be used legally in topical skin care to achieve regenerative results that were not previously possible with over-the-counter skin care products. A live demonstration of Microneedling with regenerative skin care products. Demonstrations will be conducted on the face and neck.

Dr. Song will speak about how you can use a patient’s own fat as a filler for long lasting natural facial rejuvenation and volumization. With an FDA cleared fat transfer kit, you can perform this procedure in the office without an autoclave or an operating room. A video demonstration will accompany the talk.

Bring your questions. Dr. Song and Dr. Polit have each been in aesthetic practice for over 15 years. They will talk about what has worked and what has not worked over the years, along with a discussion of their favorite technologies and products. Tips from this talk will help you avoid common mistakes that could cost you valuable time and money.

Women spend one third or their lives in menopause with an estimated 6,000 women daily or 2 million women yearly reaching menopause in the US. Fear and lack of education from health care providers combined with media sensationalism leave women confused and poorly treated during this time of life. This presentation will provide well-referenced, clinically relevant, straightforward information on women’s sex hormones, their activity, signs and symptoms of imbalance, and the relationship between hormones and diseases of aging.

Hormone testing options include serum, saliva, and urine with benefits and limitations for each. This presentation will cover testing methodologies, timing of sample collection, baseline and follow-up lab work, and hormone metabolism testing options. Genetic SNPs that influence hormone activity will also be discussed.

There are many options for BHRT supplementation with pros and cons to each. Although a thorough understanding of different modes of delivery may seem complicated, this presentation will enable participants to make evidence-based and individualized recommendations to patients focused on their goals, combined with clinical information and lab results. Appropriate monitoring of patients for complications and side effects and documenting informed consent will be covered. Emphasis will be placed on the more than 20-years of clinical experience of the presenter.

One of the main short-cuts for clinical experience is learning from other providers about their experience, especially what works and mistakes to avoid. Case presentation is critical for all providers to build knowledge and mastery in hormone optimization and managing patients. Several cases will be reviewed with participant interaction encouraged.

The Glycocalyx and Nitric Oxide: Revolutionizing Endothelial Health

Presented by Derrick DeSilva, Jr., M.D.

Open to all attendees and includes a complimentary lunch

Non-CME symposium sponsored by Calroy Health Sciences

Testosterone adequacy produces a wide range of benefits for men and women with hypogonadism. Patients note improved strength, energy, sense of well-being, muscle mass and tone, mood, erythropoiesis, and cognition. Controversies arise, however, regarding the issue of risk, many times wrapped up in myths vs. rewards. Major misconceptions have long plagued testosterone therapy. Fact or Myth: High testosterone levels result in prostate cancer. Fact or Myth: High testosterone levels result in polycythemia vera, a red blood cell tumor.  Fact or Myth: Testosterone therapy leads to cardiovascular disease, deep vein thrombosis, pulmonary emboli, and premature death. We review the origins of these complaints, review the evidence-based literature both for and against the use of testosterone in these scenarios, and present common-sense recommendations for the use of testosterone in the face of these issues. Lastly, we present a common sense history, physical and diagnostic workup for male health.

The thyroid gland produces the active thyroid hormone triiodothyronine (T3) and the store unit hormone thyroxine (T4), which regulate metabolism, growth, development, and other critical functions. Cortisol, produced by the adrenal cortex, has wide-ranging effects on stress response, immune function, and metabolism. This 60-minute presentation provides a comprehensive overview of the complex interactions between the hypothalamic-pituitary-thyroid (HPT) and the hypothalamic-pituitary-adrenal (HPA) axis, which controls cortisol release. We briefly review thyroid and adrenal gland anatomy, the feedback loops regulating thyroid and cortisol levels, and the molecular mechanisms by which cortisol influences thyroid hormone synthesis, transport, receptor binding, and gene expression. We explore states of abnormally high and abnormally low cortisol and common maladies seen when cortisol alters serum T3 and T4 concentrations. We also look at “Mr. In-Between,” the state of “normal” but not “optimal” cortisol levels and common patterns noted, including fatigue, sugar and salt cravings, and sleep cycle disruptions. Specific clinical conditions associated with cortisol-thyroid imbalances, including Addison’s disease, Cushing’s syndrome, and adrenal fatigue, are reviewed. Classic diagnostic protocols such as ACTH stimulation tests, dexamethasone suppression tests, 24-hour urine-free cortisol, thyroid function panels, imaging modalities, and advanced studies such as reverse T3 and 24-hour salivary cortisol levels are reviewed. Treatment strategies include lifestyle modifications, pharmaceuticals, botanicals, micronutrients, and diet interventions. A summary of the material is reviewed and bibliography provided. Finally, a written mind-body technique we use in our office will that participants can copy and use with their patients is included but not covered due to time constraints.

Many age management physicians are introducing Bio-Identical Hormone Therapy (BHRT) into their age management medical practices. As far as I am concerned the use of BHRT with our patients is relatively straight forward. The concern I have is that many practitioners are not well enough versed/trained in how to manage the complications of BHRT. So, what are some of the “preventative interventions” that can be taken to stave off some of these complications. Also, what baseline testing must be done in order to protect the wellbeing of the patient and allow the practitioner to sleep at night. During this presentation we will review some of the common complications of BHRT and what can be done to prevent these complications from occurring in the first place. We will also review the baseline tests that I do on all my patients before starting any form of BHRT. This is one area of medicine in which “an ounce of prevention is worth a pound of cure.”

AMMG Welcome Reception

Open to all conference attendees, spouses, and guests

Held in Conference Networking and Exhibits Center

This session will address the basics of what a peptide is, what receptor does it interact with, how do peptides work, how many peptides do we have and which hormones are peptides. Some peptides are hormones and also neurotransmitters.   In addition, how a peptide is synthesized in a lab will be reviewed. The benefits of peptides and where most of the peptides that can be obtained will be covered. (Although as of May 21, 2023 using peptides in California is prohibited, so we don’t know how one in California can obtain them.)

The history of the discovery of BPC157 will be covered and the only clinical human published study will be reviewed. The benefits and the dosing of different routes of delivery will be discussed.

Growth hormone is an essential hormone in lowering body fat, improving on lipids, keeping muscles healthy and improving on bone density. Adult growth hormone deficiency symptoms will be reviewed and the association of higher mortality with growth hormone deficiency. Unfortunately, the treatment with recombinant human growth hormone is not covered under most insurance plans and also it is cost prohibitive for most people. There is an alternative to the expensive recombinant human growth hormone mostly commonly used for boosting IGF-1 and has the advantage of inducing all five of the hGH isoforms rather just the one that is found in the synthetic form. Tesamorelin, Sermorelin and others are peptides will be reviewed.

The peptides from the Thymus gland that are immune stimulating will be covered. The studies and the dosing protocols for both these peptides If Thymus alpha 1 (TA1) and Thymulin is available in April 2024 then these peptides will be reviewed.  If these peptides are not available then other novel peptides will be discussed to improve one’s immune system.

Memory loss is a huge concern. Improving cognition is difficult but if peptides are used early with hormonal balance, improving the microbiome, and removing toxins in the body this functional medicine approach can help.  Depending on what peptides are available in April 2024 we will discuss those peptides.

Peptides can reduce inflammation and help with post-surgical pain, trauma and also with neuropathic pain. The different peptides that help with pain will be covered including the dosing protocols.

The Glycocalyx and Nitric Oxide: Revolutionizing Endothelial Health

Presented by Derrick DeSilva, Jr., M.D.

Open to all attendees and includes a complimentary lunch

Non-CME symposium sponsored by Calroy Health Sciences

There are peptides that can turn off the fibroblast cells to help produce collagen and to improve the dermis of the skin. Improving the thickness of the dermis can reduce wrinkles and also to help the skin to look younger. These peptides are very popular in any wellness practice. The top cosmeceutical peptides will be reviewed.

There are peptides that can help with cancer management. These peptides either improve the immune system or with turning on the cancer suppression genes or turning off the cancer promoting genes. Met-enkephalin and other peptides will be discussed during this session.

Autoimmune diseases are on the rise and are devastating. Balancing the immune system is one of the keys in improving autoimmune diseases. The dosing of the peptides of OGF, VIP and other peptides will be reviewed.

The pineal gland is found in vertebrates, mammals, amphibians, and in humans. Melatonin and Epitalon are both derived from the pineal gland. One of the benefits of Epitalon is that in has been shown to improve longevity in both in animals and in humans. The human clinical trials from Russia that have shown to reduce mortality and also cancer will be reviewed and the dosing protocols will also be covered.

History, Indications and Scientific Evidence-Based Rationale for the Clinical Use of IV Nutrient Therapy

This section provides the clinical guidance and basis regarding the recommended patient assessments related to IV Therapy. Review the suggested screening lab assays, understanding the clinical impact of fluid balance and highlight the special circumstances or uncommon “zebras” that providers should be aware of during patient visits.

Recommended Patient Assessments & The Hippocrates & “Zebras”

This section provides the clinical guidance and basis regarding the recommended patient assessments related to IV Therapy. Review the suggested screening lab assays, understanding the clinical impact of fluid balance and highlight the special circumstances or uncommon “zebras” that providers should be aware of during patient visits.

Components of IV Nutrition and Equipment & Set Up Procedures: IV Bottles, Bags & IV Sets

A list of supplies will be provided that are essential for the physician to use IV therapy.

Hydrate or Die-Drate: Beyond the Myers Cocktail – Part 1

Going Beyond the Myers Cocktail – In the first part of this series, we will examine the existing “popular” IV blends, delving into their benefits, indications, and applications. Additionally, we will explore the process of defining and administering IV mixes designed to optimize performance for athletes and offer immune support.

The Glycocalyx and Nitric Oxide: Revolutionizing Endothelial Health

Presented by Derrick DeSilva, Jr., M.D.

Open to all attendees and includes a complimentary lunch

Non-CME symposium sponsored by Calroy Health Sciences

Hydrate or Die-Drate: Beyond the Myers Cocktail – Part 2

Building upon the groundwork laid in Part 1, this presentation will further explore the diverse components of IV Therapy treatments. It will emphasize the optimal application of these treatments to address various patient needs, with a particular focus on combating inflammation and stress.

Clinical Pearls for the Administering IV Therapy

This section of the workshop will concentrate on the clinical insights that can distinguish your IV Clinic from competitors. It encompasses managing patient expectations, anticipating potential side effects, and providing guidance on successful implementation.

The Business of IV Therapy, Implementing it into your Clinic

An examination of the IV Therapy business landscape, covering regulations, establishment expenses, and revenue frameworks. This segment emphasizes the crucial considerations that clinical practitioners must address before launching an IV Therapy.

AMMG Welcome Reception

Open to all conference attendees, spouses and guests

Held in Conference Networking and Exhibits Center

The Glycocalyx and Nitric Oxide: Revolutionizing Endothelial Health

Presented by Derrick DeSilva, Jr., M.D.

Open to all attendees and includes a complimentary lunch

Non-CME symposium sponsored by Calroy Health Sciences

AMMG Welcome Reception

Open to all conference attendees, spouses and guests

Held in Conference Networking and Exhibits Center

Implications and Impact of Poly-Pharmacy on Aging

Presented by Derrick Desilva, Jr., M.D.

Open to all attendees and includes a complimentary breakfast

Non-CME symposium sponsored by Common Sense Supplements

Legal Insight Into Regulatory Issues Impacting Age Management Medicine: Peptides, Hormones & Supplements
Paul D. Werner, Esq.
Member of the Firm, Buttaci Leardi & Werner, Princeton, NJ

This lecture will focus on the ever-shifting regulatory framework relative to the use of peptides, hormones, and supplements by age management medicine physicians. The lecture will educate attendees on the current state of FDA regulations as it relate specifically to peptides, hormones, and supplements, and will arm attendees with the information necessary to evaluate and plan for potentials changes to those regulations in the future. Navigating regulatory compliance in the healthcare industry is always difficult, especially for age management physicians looking to employ peptides, hormones, and supplements in their practices. This lecture will help explain and simplify the processes that should be undertaken to help ensure regulatory compliance and effective use of approved products.

Break/Visit Exhibits

Break Provided by Floré Clinical

Build Your Fortress of Protection and Eliminate the Four Threats!

Presented by Art McOmber, Former FBI Special Agent

Open to all attendees and includes a complimentary lunch

Non-CME symposium sponsored by The Fortune Law Firm

Exploring Metabolic Paradigms in Cancer: From Theory to Therapeutics with a Multi-Targeted Approach
Mitchell J. Ghen, D.O., Ph.D
Family Medicine Specialist, Boca Raton, FL

An initial exploration into understanding Cancer as a Metabolic Disorder. Discussion of Metabolic hijacking as Cancer utilizes Glucose Fermentation and Amino Acid Fermentation as its main source of energy production. In addition, the Cancer Stem Cell Role and its importance in any potential Cancer protocols will be discussed. A Multi-Pronged Treatment consideration utilizing natural substances, repurposed medications, advanced therapeutic technologies, and dietary considerations will be critically looked at as a combined formidable approach to Novel Cancer Treatment options.

Current Impact of Available Age Rejuvenation Strategies, Including Apheresis, Young Plasma, and Gene Therapies Such as Follistatin Gene Therapy and Klotho Gene Therapy
Daniel L. Stickler, M.D.
Medical Director, Neurohacker Collective & Kuya Medical
Advisory Board, TruDiagnostics
Guest Lecturer, Stanford University on Nutritional Epigenetics

The latest advancements in age rejuvenation strategies, efficacy and implications of apheresis, young plasma transfusions, and groundbreaking gene therapies, including Follistatin and Klotho gene modifications.

• The underlying mechanisms of aging and the rationale behind these rejuvenation techniques.
• The effectiveness of apheresis in age-related biomarker reduction.
• An exploration of the rejuvenating potential of young plasma transfusions.
• A detailed analysis of gene therapies: the role of Follistatin in muscle mass enhancement and its potential to counteract age-related sarcopenia, and the Klotho gene’s implications in improving longevity and cognitive functions.

NON-CME lecture

AMMG Exhibit Hall Happy Hour

Join us for complimentary Margaritas, Wine and Beer

Open to all conference attendees, spouses and guests

Held in Conference Exhibit & Networking Center

“Trailblazing in Medicine: A Journey into the Next Treatment Frontiers Utilizing Exosome Therapies” explores the groundbreaking potential of exosome-based therapies in revolutionizing modern medicine. Exosomes, small extracellular vesicles secreted by cells, have emerged as powerful mediators of intercellular communication and hold immense promise for therapeutic applications across a spectrum of diseases and conditions. This talk will delve into the cutting-edge research and clinical advancements driving the development of exosome therapies. From regenerative medicine and tissue repair to cancer immunotherapy and personalized medicine, exosome-based treatments are paving the way for innovative approaches to patient care. Through a multidisciplinary lens encompassing biology, technology, and clinical translation, this presentation will illuminate the transformative impact of exosome therapies on the future of healthcare. Join us on a journey into the next treatment frontiers, where the remarkable potential of exosomes is poised to reshape the landscape of medicine and improve patient outcomes.

NON-CME lecture

Secrets of How I Took My Practice from Bankruptcy to 7-Figures

Presented by Aimee Duffy, M.D.

Open to all attendees and includes a complimentary lunch

Non-CME symposium

There exists a significant divergence in the healthspan and lifespan between women and men worldwide. While, on average, women tend to outlive men by approximately five years, post-menopause, women are also prone to developing more chronic diseases compared to men, spending a larger portion of their extended years in ill health. What underlies this discrepancy, and how does the transition from pre -menopause to post-menopause impact women’s health? In this presentation, we will delve into the multifaceted role of estrogen in health, aging, and various life stages, including pregnancy and menopause, as well as its therapeutic implications. In 2013, IgG glycosylation emerged as a pivotal biomarker of biological age. It became evident that the aging trajectories of men and women manifest distinctively when viewed through the lens of glycans. IgG glycosylation serves as a crucial modulator of low-grade sterile systemic inflammation, serving as a precursor to numerous age-related and inflammatory conditions. Alterations in glycans have been observed in over 70 conditions, spanning autoimmune, cardiometabolic, infectious, neurological diseases, and cancer, as well as natural life transitions such as (peri)menopause. Remarkably, these changes can occur up to a decade prior to the onset of symptoms and diagnosis. Studies on IgG glycosylation have demonstrated accelerated aging during perimenopause, contributing to heightened systemic inflammation, a precursor to the development of chronic diseases. Encouragingly, changes associated with accelerated biological aging have shown positive responses to hormone replacement therapy (HRT), either preventing or reversing the acceleration. Estrogen, a pivotal hormone for both men and women, exerts beneficial effects on the IgG glycome by reducing chronic inflammation. Notably, testosterone replacement therapy (TRT) has been shown to positively impact biological age, mediated through estrogen. However, when TRT is administered alongside aromatase inhibitors, thereby blocking its conversion to estrogen, no such positive effect is observed. We posit that, owing to estrogen’s anti-inflammatory effects on IgG glycome and its ability to reduce chronic inflammation, different therapeutic modalities aimed at maintaining healthy estrogen levels in both men and women (such as HRT and TRT) represent our oldest “longevity drug.” The future of this approach lies in precision medicine, leveraging the support of glycan biomarkers.

NON-CME lecture

Interaction of Fatty Acids and the Cannabinoid System
Michael Lewis, M.D., MPH, MBA, FACPM, FACN
Colonel (Retired), U.S. Army
Founder/Physician, Brain Health Education and Research Institute

There exists a complex interplay between omega-3s and omega-6s and the endocannabinoid system. The endocannabinoid system has well-established roles in neuroinflammation, synaptic plasticity and neurogenesis. The endocannabinoid system comprises cannabinoid receptors, their endogenous ligands, the endocannabinoids, and their biosynthetic and degradation enzymes. Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are essential for optimal brain development and function with and through the cannabinoid system. Omega long-chain polyunsaturated fatty acids (LCPUFA), including ARA, DHA, and EPA (eicosapentaenoic acid), are essential components of membrane phospholipids and precursors to a number of bioactive lipid mediators. Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are the most widely studied endocannabinoids and are both derived from phospholipid-bound ARA. Yet, DHA and EPA supplementation reduce AEA and 2-AG levels with reciprocal increases in levels of the analogous endocannabinoid-like DHA and EPA-derived molecules, docosahexaenoyl ethanolamide (DHEA) and eicosapentaenoyl ethanolamide (EPEA). Dietary enrichment with DHA and EPA has shown beneficial effects on learning and memory, neuroinflammatory processes, synaptic plasticity, and neurogenesis. This review contributes to the evolving landscape of concussion management by highlighting the pivotal role of targeted nutritional therapy as a therapeutic approach. These interventions can modulate neuroinflammation, enhance neuroprotection, and facilitate neurorepair. This underscores the importance of acknowledging nutrition as a complementary strategy in the multifaceted domain of concussion management and prevention.

NON-CME lecture

The Relationships between Nutrition and Cancer
John E. Lewis, Ph.D.
Voluntary Associate Professor, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL
Diplomate, Faculty Member, and Advisor, Medical Wellness Association, Houston, TX
Founder and President, Dr. Lewis Nutrition

The relationships between (bad and good) nutrition and cancer will be discussed, given that cancer is still arguably the most terrifying health-related outcome to most people.  Given the continued and growing popularity of the consumption of animal foods, problems associated with red, processed, and cooked meat, and an over-reliance on dietary protein and fat will be discussed.  Data will also be presented for the dietary patterns, foods, and nutrients that people should utilize or switch to for reducing the risk of cancer and/or how to treat it.  Cancer can actually be mitigated through proper dietary habits.

NON-CME lecture

Improving Healthspan Through Mitophagy Activation
Lisa Koche, M.D.
Family Medicine Physician, Tampa, FL
Founder & Director, Spectra Wellness Solutions
Lead Physician & Speaker, Tony Robbins Life Mastery Health Program
Jennifer Scheinman, M.S., RDN, CDN
Senior Manger Nutrition Affairs, TimeLine Nutrition

In recent years, the field of aging research has witnessed a significant upsurge in interest surrounding the role of mitochondrial health in the aging process. Mitochondria, often referred to as the “powerhouses of the cell,” play a pivotal role in energy production, metabolism, and maintaining cellular homeostasis. Understanding the intricate relationship between mitochondrial health, aging, and mitophagy (mitochondrial autophagy) holds great promise for unraveling the mysteries of longevity and age-related diseases.  This seminar will aim to shed light on the emerging knowledge regarding the interplay between mitochondrial health and age-associated chronic conditions. By delving into the mechanisms of mitophagy, the process by which damaged mitochondria are selectively degraded and recycled, we can gain valuable insights into maintaining mitochondrial quality and preserving cellular vitality. Fasting and exercise traditionally have been practices utilized to optimize mitophagy, however, new molecules, such as Urolithin A, have been identified that also induce mitophagy. Dr. Koche and Ms. Scheinman will delve into the current research on ways to activate this well-conserved quality control mechanism, exploring evidence-based protocols to support mitochondrial health. They will share clinical pearls that clinicians can utilize immediately in their practices to help their patients and clients improve their health span. mitochondrial health. They will share clinical pearls that clinicians can utilize immediately in their practices to help their patients and clients improve their health span.

NON-CME lecture

Lyme and Lyme Neuroborreliosis: Diagnosis and Treatment Based on the Latest Evidence
Andrew W. Campbell, M.D.
Editor-in-Chief, Alternative Therapies in Health and Medicine medical journal & Advances in Mind-Body Medicine Journal
Editorial Board, Integrative Medicine: A Clinician’s Journal
Medical Editor, Natural Solutions and Alternative Medicine Magazines

There are over 500,000 cases of Lyme disease diagnosed every year in the United States.  Published studies show what are the most common signs and symptoms of Lyme disease; what are the most precise tests to order and which tests are not; what is the most effective treatment for patients.