THE EPIGENETIC REVOLUTION: THE CLINICAL UTILITY AND APPLICATION FOR EPIGENETIC TESTING IN AGE MANAGEMENT WEBINAR SERIES
Aging is the number one risk factor for almost all chronic diseases. However, the wide phenotypic variation between has always kept chronological age from being a reliable clinical biomarker. As a result, aging has always been difficult to objectively assess.
Now, with the advent of new Multi-omic diagnostics such as epigenetics, transcriptomics, and proteomics, we now have ways to effectively assess patient’s aging rates and vet the effect of many anti-aging treatments. In particular, many advances have been made to epigenetic testing and the algorithms that can interpret these DNA markers to health related risks and outcomes. Now we can use these epigenetic algorithms to assess immune system function, telomere length, senescence, instantaneous aging rate, and of course how all of these metrics relate to the risk of developing chronic disease.
Additionally, unlike DNA, changes can be made to reverse the signs of epigenetic aging as a way to improve health. As a result, we can finally treat and test aging with a single test. n this lecture series we will talk about the history of this new field, how many are using it, and the best ways to reverse epigenetic aging.
Curriculum
Every cell in the body has the same DNA, however, it is our cells’ epigenetic programming that gives our cells their individual phenotypes. Through new developments in computer learning, we now have a way to read these epigenetic markers as ways to predict disease and improve health. Perhaps no area of medicine has benefited more from these developments than the area of aging medicine. This is because there are amazingly accurate biological age measurements which can be used as an objective measure of the aging process and can successfully quantify the effect of age management interventions. In this lecture, we will discuss the new ways to read epigenetics for age related biomarkers.
Luis Martinez, M.D.
President, Regenera Global, Ponce, Puerto Rico
President, XanoGene Clinic, San Juan, Puerto Rico
While epigenetic age is a breakthrough therapy for preventative health, the benefits of methylation data exceed way beyond aging. In this lecture we will discuss how epigenetic methylation can give us insights on other aspects of aging such as the instantaneous rate of aging, telomere length through epigenetics, senescence, and stem cell depletion. We will also discuss where the field is going in the next 10 years and how it will change functional medicine.
Chris Turnpaugh, D.C., DACNB
CEO & President, Turnpaugh Health and Wellness Center Functional Medicine, Chiropractic Neurology, Mechanicsburg, PA
Clinician, Health for You, Millers Natural Foods Amish Clinic
As epigenetics research continues to expand to more accurately predict health, we are also learning about how to structure medical interventions to facilitate the best health changes for patients. In this lecture, we will discuss validated interventions to change epigenetic aging, epigenetic rate of aging, and other methylation loci.
Larry Siegel, APRN, MSNN
Founder, Yunique Medical Services
FACULTY
- President, Regenera Global, Ponce, Puerto Rico
- President, XanoGene Clinic, San Juan, Puerto Rico
Dr. Luis MartĂnez is a Regenerative Medicine, Anti-aging and Cell Therapy specialist, clinical researcher and biomedical consultant. He earned his medical degree at The Ponce School of Medicine and completed his residency training at the prestigious University of Pennsylvania. He also completed an Advanced Training Course in Stem Cells in Cancer at the Ponce Health Sciences University/ Magee Research Institute consortium. He is board certified in Clinical Lipidology. Dr. Martinez holds a Master of Public Health with a concentration in Epidemiology and is fellowship trained in Biosecurity. He is the president of Xanogene Clinic, which specialized in Regenerative and Age Management Medicine. He also founded and presides over Regenera Global, a multinational corporation specializing in biotech product development, research, and clinical consulting. Dr. Martinez is also Co-Founder of the Clinical Peptide Society, a US based professional organization aimed at educating physicians and advancing the use of peptide therapeutics. Alongside with the Age Management Medicine Group, he and his colleague have developed the world’s first Peptide Certification Program and have so far trained and educated over 400 physicians. He additionally trains physicians in other aspects of Regenerative and Age Management Medicine through his physician training portal Elite Group MD. Dr. Martinez recently founded, alongside various colleagues the Senolytic Therapy Network. It is the first professional organization dedicated to advancing the science and clinical applications of senolytic therapies.
FACULTY DISCLOSURE: No Relevant Relationships with a Commercial Interest to Disclose
- CEO & President, Turnpaugh Health and Wellness Center Functional Medicine, Chiropractic Neurology, Mechanicsburg, PA
- Clinician, Health for You, Millers Natural Foods Amish Clinic
Chris Turnpaugh is a skilled practitioner whose primary focus is on finding and addressing the root cause of disease. He graduated from LIfe College of Chiropractic and received his post-doctorate in functional neurology. His passion for functional medicine led him to open the Turnpaugh Health and Wellness Center in 1999. He has extensive experience in supporting patients who are dealing with chronic, autoimmune and neurological health conditions. He has a vast history of personal experience in supporting Lyme disease, autoimmune conditions, Fragile X Syndrome and pediatric neurological conditions, thyroid disease, hormonal conditions and more. With over 25 years of clinical experience, he has started a program named “LIVEgevity” to maximize health potential in the aging population. He has been asked to consult with several national laboratories to further understand the value of testing relative to healthy aging. Dr. Turnpaugh teaches providers across the country about blood chemistry, the aging physiology, thyroid conditions, brain disorders and other functional medicine trainings. In his free time, Dr. Turnpaugh enjoys spending time outside, hiking, swimming, watching college football and spending time with his family, his wife, Heather, and their four children.
FACULTY DISCLOSURE: No Relevant Relationships with a Commercial Interest to Disclose
- Founder, Yunique Medical Services
Larry Siegel is an APRN (Advanced Practice Registered Nurse) and has been practicing medicine for 19 years. He founded Yunique Medical in 2016 and now offers his services at several clinics in Central Florida, including Fruitland Park (The Villages), Ocala, Daytona, and Orlando.
Larry is utterly dedicated to his profession and seeks continuous improvement. He has a diversity of specialist skills, certifications, and knowledge that make him the best in his field. As a SottoPelle certified physician, he specializes in hormone therapy and delivers a choice of sustainable treatments that address the underlying cause of his patients’ symptoms. Larry is a Peptide Mastermind and Clinical Fellow as well as an Elite Cellular and Performance Mastermind Fellow. He practices functional medicine, provides precision therapies, is an epigenetic expert, and is devoted to giving the highest quality patient-centered care. If that wasn’t enough Larry is also a committed clinical researcher. His passion and goals are all about producing a life-changing experience for his patients and improving their quality of life.
FACULTY DISCLOSURE: No Relevant Relationships with a Commercial Interest to Disclose
Course Information
Disclosure of Conflict of Interest
Conference Planning Committee
Mary L. Corry, R.N. – No Relevant Relationships with a Commercial Interest to Disclose
Mark L. Gordon, M.D. –Â No Relevant Relationships with a Commercial Interest to Disclose
Rob A. Kominiarek, D.O. – No Relevant Relationships with a Commercial Interest to Disclose
Cesar M. Pellerano, M.D. – No Relevant Relationships with a Commercial Interest to Disclose
John Rush, M.D. –Â No Relevant Relationships with a Commercial Interest to Disclose
George Shapiro, M.D. –Â Â No Relevant Relationships with a Commercial Interest to Disclose
No member of The Foundation for Care Management or the Age Management Medicine Group has any relevant financial relationships to disclose in regards to this activity.
Faculty
Luis Martinez, M.D. – No Relevant Relationships with a Commercial Interest to Disclose
Larry Siegel, APRN – No Relevant Relationships with a Commercial Interest to Disclose
Chris Turnpaugh, DC, DACNB No Relevant Relationships with a Commercial Interest to Disclose
Acknowledgement of Financial Commercial Support
Unrestricted educational grant provided by TruDiagnostic & Tailor Made Compounding
Acknowledgement of In-Kind Commercial Support
No in-kind commercial support was received for this educational activity.
Learning Objectives:
- Describe the essential scientific evidence-based information for methods of using epigenetic markers to determine biological age, and ways to predict disease and improve patient health and outcomes.
- Describe and discuss how epigenetic methylation can provide insights into aspects of aging such as rates of aging and telomere length
- Discuss new scientific evidence-based interventions such as epigenetic rate of aging derived from genetic testing to facilitate and provide superior patient care and impact patient outcomes.